2005 Fiscal Year Final Research Report Summary
| Project/Area Number |
14550140
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fluid engineering
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| Research Institution | Waseda University (2005)
Yamagata University (2002-2004) |
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Principal Investigator |
NAITOH Ken Waseda University, Faculty of Science and Engineering, Professor, 理工学術院, 教授 (30323174)
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| Project Period (FY) |
2002 – 2005
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| Keywords | Bioinfomatics / Biofluid Dynamics |
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| Research Abstract |
Life uses two types of nitrogenous bases for DNA and RNA, purine and pyrimidine. Then, base pairs of purine-pyrimidine are mainly used, while pairs of identical bases are also observed. The size ratio of base pairs are between 1.0 and about 1.5. Why are the present size ratios employed? We tried to clarify the reason by using a fluid dynamic model, stochastic computer models, fundamental experiments, and some databases.
As the result, we think the diversity between 1.0 and 1.5 brings us flexibility. There will be not the best size ratio which brings highest replication speed. Then, we found that asymmetry of size ratio leads to complex shapes of RNAs. The range between 1.0 and about 1.5 is described by the n-th root of n.
The present research also brings us the insight that Thermophiles preferring about 80 ℃ may eat some materials inside fuel cell systems.
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