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2003 Fiscal Year Final Research Report Summary

Development of practical system for high-speed magnetic resonance elastography

Research Project

Project/Area Number 14570854
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

MATSUDA Tetsuya  Kyoto University, Graduate School of Informatics, Professor, 情報学研究科, 教授 (00209561)

Co-Investigator(Kenkyū-buntansha) SUGA Mikio  Nara Institute of Science and Technology, Graduate School of Information Science, Research Associate, 情報科学研究科, 助手 (00294281)
MINATO Kotaro  Nara Institute of Science and Technology, Graduate School of Information Science, Professor, 情報科学研究科, 教授 (00127143)
MIZUTA Shinobu  Kyoto University, Graduate School of Informatics, Research Associate, 情報学研究科, 助手 (40314265)
AMANO Akira  Kyoto University, Graduate School of Informatics, Assistant Professor, 情報学研究科, 助教授 (60252491)
Project Period (FY) 2002 – 2003
KeywordsMagnetic Resonance Elastography / high-speed MRI / phase contrast method / oscillation system / preparation pulse
Research Abstract

Magnetic resonance elastography (MRE) can provide quantitative measurements of tissue elasticity by visualizing the strain waves applied from the body surface. Though MRE is expected to be a powerful diagnostic tool for tissue characterization, its long acquisition time limits the practical application to the area such as brain, extremities, and breast, where respiratory motion was not necessarily considered. To realize in vivo measurement of tissue elasticity in human abdomen, we aimed to develop a high speed MRE acquisition method by introducing our original technique of phase velocity encoding that could be combined with various high speed MR imaging methods as preparation pulses. The technique translated the velocity encoded phase shift into the longitudinal magnetization and the velocity information was retrieved from the signal intensity after the image acquisition. In this research project, we also designed an oscillation system that generates strain waves appropriate to calculate the elasticity from the acquired images.
Introduction of our original technique of phase velocity encoding to a high speed MR imaging method successfully acquired MRE images during a single breath-hold period. The oscillation system we proposed in this research project was a bed-type oscillator on which patients rested. We constructed a prototype of table oscillator and MRE images obtained from an elastic phantom on the table oscillator demonstrated that flat strain waves were generated. Since pure transverse waves were generated independently from longitudinal wave components, shear modulus of the phantom could be calculated from the obtained MRE images without contamination of Young' s modulus. While tissue elasticity of abdominal organ has not been obtained yet, essential methodology for abdominal MRE was established in this research project.

  • Research Products

    (12 results)

All Other

All Publications (12 results)

  • [Publications] Takenori Oida: "Magnetic Resonance Elastography : in vivo Measurements of Elasticity for Human Tissue"IEEE Computer Society. (In Press). (2004)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mikio Suga: "Measurement of In Vivo Local Shear Modulus Using MR Elastography Multiple-Phase Patchwork Offsets"IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 50・7. 908-915 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takenori Oida: "Bed-Type oscillator for MR Elastography"Proc.Intl.Soc.Mag.Reson.Med.. 11. 1773 (2004)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 下垣徹: "3次元反力取得・表示システムを用いた仮想物体と実物体の力覚情報比較"日本バーチャルリアリティ学会論文誌. 8・22. 145-154 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 松田哲也: "循環器MRIの特徴:心拍動機と高速撮影"日本磁気共鳴医学会雑誌. 23・4. 120-130 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 菅幹生: "MR elastography法-MRIを用いた定量的触診-"映像情報メディカル臨時増刊号Routine Clinical MRI 2004 Book. 35・15. 96-70 (2003)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takenori Oida: "Magnetic Resonance Elastography: in vivo Measurements of Elasticity for Human Tissue"IEEE Computer Society. (In Press). (2004)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mikio Suga: "Measurement of In Vivo Local Shear Modulus Using MR Elastography Multiple-Phase Patchwork Offsets"IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING. 50・7. 908-915 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takenori Oida: "Bed-Type oscillator for MR Elastography"Proc Intl.Soc.Mag.Reson.Med.. 11. 1773 (2004)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Toru Shimogaki: "Comparing force information from a real object with that from a virtual object using a system for measuring and describing 3D force feedback"Transactions of the Virtual Reality Society of Japan. 8・22. 145-154 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tetsuya Matsuda: "ECG Gating in Cardiac MRI"Japanese Journal of Magnetic Resonance in Medicine. 23. 120-130 (2003)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mikio Suga: "MR elastography -Quantitative Palpation by using MRI -"A monthly Journal of Medical Imaging and Information. 35・15. 96-100 (2003)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2005-04-19  

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