SII (Secondary somatosensory cortex) can be separated into two areas: Dorsal side of 511 may participate in pain perception

2003 Fiscal Year Final Research Report Summary

• Project/Area Number: 14571433
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Anesthesiology/Resuscitation studies
• Research Institution: OSAKA University
• Principal Investigator: SHIBATA Masahiko Osaka University, Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 (50216016)
• Co-Investigator(Kenkyū-buntansha): HAYASHI Yukio Osaka University, Graduate School of Medicine, Associate Professor, 医学系研究科, 助教授 (60294063) ; MASHIMO Takashi Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授 (60157188) ; INOUE Takaya Osaka University, Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 (00335358) ; MIYAUCHI Satoshi Kansai Advanced Research Center, Professor, 室長
• Project Period (FY): 2002 – 2003
• Keywords: allodynia / complex regional pain syndrome / f MRI / neuro-imaginging

Research Abstract

Although evidence shows that the secondary somatosensory cortex (SII) responds to tactile perception and pain, the location where this occurs and the role of SII are still unclear. We used functional MRI to evaluate activity in response to dynamic and static mechanical nociceptive stimulation. Dynamic nociceptive stimulation activated dorsal and ventral sides of SII. Static nociceptive stimulation activated only the dorsal side. Our results show that SIi is functionally divided into at least two different areas; the dorsal side is activated in pain perception and the ventral side of SII may react to changing of tactile stimulation.