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2003 Fiscal Year Final Research Report Summary

The effect of dioxine on allergic rhinitis

Research Project

Project/Area Number 14571605
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionYamagata University

Principal Investigator

OHTA Nobuo  Yamagata University, Otolaryngology, Lecturer, 医学部, 講師 (20282212)

Project Period (FY) 2002 – 2003
Keywordsdioxine / neutrophils / allergy
Research Abstract

Although the environmental contaminant 2,3,7,8-tetrachlordibenzo-p-dioxin (TCDD), via its interaction with the Ah receptor is an extremely potent carcinogen and immunosuppressive agent in experimental animal, its possible actions on neutrophil function have not been determined. In addition to their importance against infectious microorganisms, neutrophils have been implicated in antitumor resistance. The present study examined the effects of in vitro exposure to TCDD on human neutrophils. TCDD upregulate the expression of adhesion molecule on neutrophils dose dependent manner.

  • Research Products

    (2 results)

All 2002

All Journal Article (2 results)

  • [Journal Article] 環境ホルモン(ダイオキシン)の好中球接着に及ぼす影響2002

    • Author(s)
      古武 洋, 太田伸男, 青柳 優
    • Journal Title

      耳鼻咽喉科免疫アレルギー 20(2)

      Pages: 124-125

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] The effects of Dioxin on human peripheral Neutrophil adherence.2002

    • Author(s)
      Yoshitake H, Ohta N, Aoyagi M
    • Journal Title

      J.J.I.A.O 20(2)

      Pages: 124-125

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 2007-12-13  

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