2003 Fiscal Year Final Research Report Summary
Influences of stellate ganglion block and near-infrared irradiation around stellate ganglion on the activity of brain cell
| Project/Area Number |
14571903
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Kagoshima University |
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Principal Investigator |
YOKOYAMA Kozo Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 (80191518)
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| Project Period (FY) |
2002 – 2003
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| Keywords | brain wave / stellate ganglion / near-infrared ray / stellate ganglion block / 90% spectral edge frequency / slectral median frequency / power spectral analysis |
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| Research Abstract |
In this study, it was investigated whether stellate ganglion block(SGB)or several doses of linearly near-infrared irradiation around stellate ganglion(SGR)had some influences on brain cell activity in frontal cortex 30 mm after treatment.Brain waves were measured and performed Fourier transform. Then, we tried to examine changes of 90% spectral edge frequency(SEF90), spectral median frequency(SMF)and relative power of brain waves following treatment.
In the SGB, relative power of fast activity, SEF90 values and SMF values were increased 15 min after SGB on the unblocked side and increased between 20 mm and 30 mm by degrees on the blocked side.In the SGR groups between 90 J/cm^2 and 180 J/cm^2, relative power of fast activity, SEF90 values and SMF values increased on bilateral sides.Therefore, it was suggested that both SGB and these doses of SGR activated brain cells.Especially, relative power of theta-wave increased in the dose of 90 J/cm^2 SGR group more than in SGB group.On the other hand, in 360 J/cm^2 SGR group relative power of fast activity, SEF90 values and SMF values were decreased.It was suggested that 360 J/cm^2 SGR had sedative action on brain cell activity as compared with 90-180 J/cm^2 SGR.
It was concluded that 90-180 J/cm^2 SGR had the same stimulatory action as SGB.This SGR treatment is non-invasive for patients and 90-180 J/cm^2 SGR will be applied for the treatment of brain activation in the near friture.In addition, there is a possibility that 360 J/cm^2 SGR will suppress hyperexcitability of brain cells and then normalize them.
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