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2007 Fiscal Year Final Research Report Summary

Intelligent Assistance in Diagnosis of Multi-dimensional Medical Images

Research Project

Project/Area Number 15070101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionTokyo University of Agriculture and Technology

Principal Investigator

KOBATAKE Hidefumi  Tokyo University of Agriculture and Technology, of Agri. and Tech., Headquarters, President (80013720)

Co-Investigator(Kenkyū-buntansha) TAMURA Shinichi  Osaka Univ., Graduate School of Medicine, Professor (30029540)
NIKI Noboru  The Univ. of Tokushima, Institute of Technology and Science, Graduate school, Professor (80116847)
SUENAGA Yasuhito  Nagoya Univ., Graduate School of Information Science, Professor (60293643)
FUJITA Hiroshi  Gifu Univ., Graduate School of Medicine, Professor (10124033)
SUGIMOTO Naozo  Kyoto Univ., Graduate School of Information, Professor (20196752)
Project Period (FY) 2003 – 2006
Keywordscomputer aided diagnosis / pattern recognition / multi-organ / multi-disease / visualization / CT image
Research Abstract

The objective of this research project is to develop a multi-organ, multi-disease CAD system that incorporates anatomical knowledge of the human body and diagnostic knowledge of various types of diseases.
Digital atlases of human anatomy (DAHA) have been developed. Based on them various methods of segmentation of organs in the chest and/or abdominal 3D CT images have been developed. They include the bronchus, the blood vessels in the lung area, the diaphragm, the heart, the coronary artery, the stomach wall, the liver, the spleen, the left and right kidneys, the gallbladder, the pancreas, the colon, the portal vein (PV) between the spleen and liver, the esophagus, the abdominal aorta, and the inferior vena cava (IVC).
The characteristics of abnormal regions depend on the type of disease. In order to identify these abnormalities, diagnostic knowledge of various types of diseases is essential. A database of such diagnostic knowledge on the major organs in chest and/or abdominal region, i. e. a digital representation of diagnostic knowledge (DRDK), has been developed.
The DANA and the DRDK are large databases that can be achieved by the collaboration of several research groups. Various types of segmentation methods, organ modeling methods, lesion detection methods, diagnostic methods, etc., must be integrated into one system to develop a multi-organ, multi-disease CAD system. A common platform that can integrate all of those plug-in units has been developed. It is called Pluto. And a prototype of a comprehensive CAD system for multi-organ and multi-disease has been constructed on this platform.
These results suggest that the goal of the research project has been achieved.

  • Research Products

    (25 results)

All 2008 2007 2006 2005 2004 Other

All Journal Article (17 results) (of which Peer Reviewed: 8 results) Presentation (4 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Automated estimation of the upper surface of the diaphragm in 3-D CT images2008

    • Author(s)
      ^*X. Zhou. T. Hara, H, Fujita, R. Yokoyama, H. Cheng, T. Kiryu, H. Hoshi
    • Journal Title

      IEEE Transactions on Biomedical Engineering 55

      Pages: 351-353

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Automated estimation of the upper surface of the diaphragm in 3-D CT images2008

    • Author(s)
      X. Zhou, T. Hara. H. Fujita, R. Yokoyama, H. Cheng, T. Kiryu, H. Hoshi
    • Journal Title

      IEEE Transactions on Biomedical Engineering Vol. 55, No. 1

      Pages: 351-353

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] カスケード識別による乳房X線像上の悪性腫瘤影識別処理の高度化2007

    • Author(s)
      根本充貴, 清水昭伸, 小畑秀文
    • Journal Title

      Medical Imaging Technology 25

      Pages: 121-130

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Recovery of respiratory motion and deformation of the liver using laparoscopic freehand 3D ultrasound system2007

    • Author(s)
      Masahiko Nakamoto. Hiroaki Hirayama, Yoshinobu Sato
    • Journal Title

      Medical Image Analysis 11

      Pages: 429-442

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] SAKURA-viewer : Intelligent order history viewer based on two-viewpoint architecture2007

    • Author(s)
      S. Toyota, ^*N. Niki, H. Nishitani
    • Journal Title

      IEEE Transactions on Information Technology in Biomedicine 11

      Pages: 141-152

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Interferometer-based phase-contrast X-ray CT of colon cancer specimens : Comparative study with 4.74 tesla MRI and optical microscopy2007

    • Author(s)
      T. Takeda, J. Wu, Thet-Thet-Lwin, A. Yoneyama, K. Hyodo, Y. Matsuda, K. Kose
    • Journal Title

      J. Compt. Assist. Tomogr. 31

      Pages: 214-217

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Recovery of respiratory motion and deformation of the liver using laparoscopic freehand 3D ultrasound system2007

    • Author(s)
      Masahiko Nakamoto, Hiroaki Hirayama, Yoshinobu Sato, Kozo Konishi, Yoshihiro Kakeji, Makoto Hashizume, Shinichi Tamura
    • Journal Title

      Medical Image Analysis vol. 11, no. 5

      Pages: 429-442

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] SAKURA-viewer : Intelligent order history viewer based on two-viewpoint architecture2007

    • Author(s)
      S. Toyota, *N. Niki, H. Nishitani
    • Journal Title

      IEEE Transactions on Information Technologyin Biomedicine Vol. 11, No. 2

      Pages: 141-152

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Interferometer-based phase-contrast X-ray CT of colon cancer specimens : Comparative study with 4.74 tesla MRI and optical microscopy2007

    • Author(s)
      T. Takeda. J, Wu. Thet-Thet-Lwin, A. Yoneyama, K. Hyodo, Y. Matsuda, K. Kose
    • Journal Title

      J. Compt. Assist. Tomogr 31

      Pages: 214-217

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Characterization of 133Xe gas washout in pulmonary emphysema with dynamic 133Xe SPECT functional images2006

    • Author(s)
      Suga K, Kawakami Y, Yamashita T, Zaki M, ^*Matsunaga N
    • Journal Title

      Nuclear Medicine Communications 27

      Pages: 71-80

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] A method for bronchoscope tracking by combining a position sensor and image registration2006

    • Author(s)
      Daisuke Deguchi, Kenta Akiyama, Kensaku Mori, Takayuki Kitasaka, Yasuhito Suenaga, Calvin R Maurer Jr, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori
    • Journal Title

      Computer Aided Surgery 11

      Pages: 109-117

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] A Novel Registration Method for Interval Change Detection between Two Chest X-ray Images With Different Rotation Angles2006

    • Author(s)
      Akinobu Shimizu, Yoshie Matsuo, Hhidefumi Kobatake
    • Journal Title

      Academic Radiology Vol. 13, Issue 4

      Pages: 503-511

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Characterization of 133Xe gas washout in pulmonary emphysema with dynamic 133Xe SPECT functional images2006

    • Author(s)
      SugaK, KawakamiY, Yamashita T, ZakiM, Matsunaga N
    • Journal Title

      Nuclear Medicine Communications 27(1)

      Pages: 71-80

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Extraction and Quantitative Analysis of Aneurismal Aorta for Aiding Endovascular Stent Grafting2004

    • Author(s)
      H. Imamura, ^*N. Sugimoto, s. Eiho. S. Urayama. K. Ueno, K. Inoue
    • Journal Title

      Systems and Computers in Japan 35

      Pages: 58-67

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
  • [Journal Article] Extraction and Quantitative Analysis of Aneurismal Aorta for Aiding Endovascular Stent Grafting2004

    • Author(s)
      H. Imamura, *N. Sugimoto, S. Eiho, S. Urayama. K. Ueno, K. Inoue
    • Journal Title

      Systems and Computers in Japan Vol. 35, No. 3

      Pages: 58-67

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] A method for bronchoscope tracking by combining a positionsensor and image registration2004

    • Author(s)
      Daisuke Deguchi, Kenta Akiyama, Kensaku Mori. Takavuki Kitasaka, Yasuhito Suenaga, Calvin R Maurer Jr, Hirotsugu Takabatake, Masaki Mori, Hiroshi Natori
    • Journal Title

      Computer Aided Surgery Vol. 11, No. 3

      Pages: 58-67

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Quantitative assessment of the influence of anatomic noise on the detection of subtle lung nodulein digital chest radiography using fractal-feature distance

    • Author(s)
      Kuniharu Imai, Mitsuru Ikeda, Yukihiro Enchi, Takanaga Niimi
    • Journal Title

      European Journal of Radiology (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Detection of architectural distortion on mammograms based on characteristics of the mammary grand2007

    • Author(s)
      Mitsutaka Nemoto, Soshi Honmura, Akinobu Shimizu, Hidefumi Kobatake, Shigeru Nawano
    • Organizer
      International Journal of Computer Assisted Radiology and Surgery
    • Place of Presentation
      Berlin
    • Year and Date
      20070600
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Automatic Liver Segmentation Method based on Maximum A Posterior Probability Estimation and Level Set Method2007

    • Author(s)
      Daisuke Furukawa, Akinobu Shimizu, Hidefumi Kobatake
    • Organizer
      Proc. of Workshop on 3D segmentation in the clinic : A grand challenge
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      20070000
    • Description
      「研究成果報告書概要(和文)」より
  • [Presentation] Automatic Liver Segmentation Method based on Maximum A Posterior Probability Estimation and Level Set Method2007

    • Author(s)
      Daisuke Furukawa, Akinobu Shimizu, Hidefumi Kobatake
    • Organizer
      Proc. of Workshop on 3D segmentation in the clinic : A grand challenge, pp. 117-124
    • Year and Date
      20070000
    • Description
      「研究成果報告書概要(欧文)」より
  • [Presentation] Thoracoscopic surgical navigation system for cancer localization in collapsed lung based on estimation of lung deformation2007

    • Author(s)
      Nakamoto M, Aburaya N, Sato Y, Konishi K, Yoshino I, Hashizume M, Tamura S
    • Organizer
      Proc. Tenth International Conference on Medical Image Computing and Computer Assisted Intervention, Part II, pp. 68-76
    • Year and Date
      20070000
    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] 画像情報処理(I)2005

    • Author(s)
      鳥脇純一郎, 長谷川純一, 清水昭伸, 平野靖
    • Total Pages
      139
    • Publisher
      日本エム・イー学会
    • Description
      「研究成果報告書概要(和文)」より
  • [Remarks] 「研究成果報告書概要(和文)」より

    • URL

      http://www.future-cad.org/fcad/index.htm

  • [Patent(Industrial Property Rights)] 特許2006

    • Inventor(s)
      森健策, 北坂孝幸
    • Industrial Property Rights Holder
      名古屋大学
    • Industrial Property Number
      特願2006-128681号
    • Filing Date
      20060000
    • Description
      「研究成果報告書概要(和文)」より
  • [Patent(Industrial Property Rights)] 特許2005

    • Inventor(s)
      真田茂, 田中利恵
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      特願2005-180758
    • Filing Date
      20050000
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2010-06-09  

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