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2005 Fiscal Year Final Research Report Summary

Integrated research on coronary plaque imaging for the establishment of preventive radiology.

Research Project

Project/Area Number 15209039
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionGraduate School of Medical Science, Kyoto Prefectural University of Medicine

Principal Investigator

NISHIMURA Tsunehiko  Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Professor, 医学研究科, 教授 (70237733)

Co-Investigator(Kenkyū-buntansha) USHIJIMA Yo  Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 講師 (20275209)
YAMADA Kei  Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 講師 (80315960)
KIZU Osamu  Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 助手 (70305598)
ITO Hirotoshi  Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Radiology, Assistant Professor, 医学研究科, 助手 (60360038)
Project Period (FY) 2003 – 2005
KeywordsPreventive Radiology / Coronary plaque / Multi slice CT / MR / Molecular Imaging / Fusion image
Research Abstract

There are few researches of preventive radiology on coronary sclerotic imaging, since many researches have been focused on ischemic heart disease until now. Recently, higher advance of multi-slice CT and MRI has made visualization of coronary arterial involvement including sclerosis and plaque. Furthermore, PET and SPECT has made active plaque deposition as molecular imaging. Our research has focused on integrated approach of coronary animal and human plaque imaging by CT/MR(anatomy) and PET/SPECT(function). In conclusion, coronary plaque imaging has been established by our integrated research. Furthermore, early detection of coronary sclerosis before ischemic heart disease(coronary stenosis) has made early cholesterol lowering therapy and decrease of medical fee and promotion of QOL.

  • Research Products

    (11 results)

All 2005 2004 2003

All Journal Article (10 results) Book (1 results)

  • [Journal Article] Imaging of lesions in a murine rheumatoid arthritis model with a humanized anti-interleukin-6 receptor antibody.2005

    • Author(s)
      Sugimoto K, Nishimoto N, Yoshizaki K, Nishimura T 他1名.
    • Journal Title

      Ann Nucl Med 19

      Pages: 261-266

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Imaging of lesions in a murine rheumatoid arthritis model with a humanized anti- interleukin-6 recepter antibody.2005

    • Author(s)
      Sugimoto K, Nishimoto N, Kishimoto T, Yoshizaki K, Nishimura T.
    • Journal Title

      Ann Nucl Med 19

      Pages: 261-266

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Myocardial scintigraphy using a fatty acid analogue detects coronary artery disease in hemodialysis patients.2004

    • Author(s)
      Nishimura M, Hashimoto T, Nishimura T, Ono T 他6名.
    • Journal Title

      Kidney Int 66

      Pages: 811-819

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Stroke patients' evolving symptoms assessed by tractography.2004

    • Author(s)
      Yamada K, Ito H, Nakamura H, Mori S, Nishimura T 他8名.
    • Journal Title

      J Magn Reson Imaging 20

      Pages: 923-929

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Myocardial scintigraphy using a fatty acid analogue detects coronary artery disease in hemodialysis patients.2004

    • Author(s)
      Nishimura M, Hashimoto T, Kobayashi H, Fukuda T, Okino K, Yamamoto N, Fujita H, Inoue N, Nishimura T, Ono T.
    • Journal Title

      Kidney Int 66

      Pages: 811-819

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Stroke patients' evolving symptoms assessed by tractography.2004

    • Author(s)
      Yamada K, Ito H, Nakamura H, Kizu O, Akada W, Kubota T, Goto M, Konishi J, Yoshikawa K, Shiga K, Nakagawa M, Mori S, Nishimura T.
    • Journal Title

      J Magn Reson Imaging 20

      Pages: 923-929

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Impaired cardiac response to exercise in post-menopausal women : relationship with peripheral vascular function.2003

    • Author(s)
      Yoshioka J, Node K, Hasegawa S, Hori M, Nishimura T 他5名.
    • Journal Title

      Nucl Med Commun 24

      Pages: 383-389

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 99mTc-hynic-annexin V imaging to evaluate inflammation and apoptosis in rats with autoimmune myocarditis.2003

    • Author(s)
      Tokita N, Hasegawa S, Strauss HW, Nishimura T 他4名.
    • Journal Title

      Eur J Nucl Med Mol Imaging 30

      Pages: 232-238

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Impaired cardiac response to exercise in post-menopausal women : relationship with peripheral vascular function.2003

    • Author(s)
      Yoshioka J, Node K, Hasegawa S, Paul AK, Mu X, Maruyama K, Nakatani D, Kitakaze M, Hori M, Nishimura T.
    • Journal Title

      Nucl Med Commun 24

      Pages: 383-389

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 99mTc-hynic-annexin V imaging to evaluate inflammation and apoptosis in rats with autoimmune myocarditis.2003

    • Author(s)
      Tokita N, Hasegawa S, Maruyama K, Izumi T, Blankenberg FG, Tait JF, Strauss HW, Nishimura T.
    • Journal Title

      Eur J Nucl Med Mol Imaging 30

      Pages: 232-238

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] 機能・代謝画像診断法と分子画像2003

    • Author(s)
      西村 恒彦
    • Total Pages
      340
    • Publisher
      南山堂
    • Description
      「研究成果報告書概要(和文)」より

URL: 

Published: 2007-12-13  

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