2005 Fiscal Year Final Research Report Summary
The study of a new method of sentinel node detection in breast cancer using contrast-enhanced ultrasonography
| Project/Area Number |
15300186
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | JICHI MEDICAL SCHOOL |
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Principal Investigator |
OMOTO Kiyoka JMS, School of Medicine, Assistant Professor, 医学部, 講師 (90306118)
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| Co-Investigator(Kenkyū-buntansha) |
TANIGUCHI Nobuyuki JMS, School of Medicine, Associate Professor, 医学部, 助教授 (10245053)
ITOH Kouichi JMS, School of Medicine, Professor, 医学部, 教授 (60095007)
HOZUMI Yasuo JMS, School of Medicine, Associate Professor, 医学部, 助教授 (50260831)
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| Project Period (FY) |
2003 – 2005
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| Keywords | contrast-enhanced ultrasound / sentinel lymph node / breast cancer / albumin / lymph node metastasis / animal experiment / clinical evaluation / dye-guided method |
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| Research Abstract |
In animal and clinical study using US contrast-enhanced with 25% albumin, SLNs were identified in all cases. The pathologic findings suggested our method may represent a new modality for SLN detection.
The another animal study by CE-US using a mixture of sulphan blue and hydroxyethylated starch indicated a good result, and its clinical study is planning.
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