2004 Fiscal Year Final Research Report Summary
Effects of Food Restriction during Puberty and Pregnant Period on the Maternal Body and Growth of Progeny
| Project/Area Number |
15500541
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Nara Women's University |
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Principal Investigator |
MIZUKAMI Taiko Nara Women's University, Faculty of Human Life and Environment, Professor, 生活環境学部, 教授 (50031688)
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| Project Period (FY) |
2003 – 2004
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| Keywords | puberty / Pregnant period / food restriction / growth |
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| Research Abstract |
The effects of food restriction in rats through puberty or puberty- pregnancy period on the maternal body and growth of the progeny were studied. We prepared three groups of 7 weeks old female rats : one group (CC group) fed ad libitum (10% casein and 10% soy protein diet) and two food-restricted groups fed 30% less than the CC group through puberty (CR group) or puberty-pregnancy period (RR group). The food-restricted and ad libitum- fed animals were pair-fed. All groups of pregnant rats maintained pregnancy and performed normal delivery and lactation. Food restriction through puberty did not affect remarkably on the maternal body and growth of the newborn pups and weaning progeny of RC group in comparison with the CC group. Food restriction through puberty-pregnancy period reduced the maternal body weight gain and the abdominal fat weight of the RR group when compared with the CC group. The body weight and organ weight of newborn pups in the RR group were significantly lower than those of the CC group. At 3 weeks after birth retarded growth was observed in the weaning progeny of the RR group in comparison with the CC group. We conclude that the food restriction through puberty-pregnant period markedly affected the maternal body and growth of the progeny.
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