2004 Fiscal Year Final Research Report Summary
CANCER RISK ASSESSMENT OF POLYCYCLIC AROMATIC HYDROCARBONS BY EPIDEMIOLGIC STUDIES USING BIOMARKERS
| Project/Area Number |
15590530
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Hygiene
|
|---|
| Research Institution | NATIONAL CANCER CENTER |
|---|
Principal Investigator |
HANAOKA Tomoyuki NATIONAL CANCER CENTER, EPIDEMIOLOGY AND PREVENTION DEVISION, SECTION HEAD, 予防研究部, 室長 (00228503)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
ICHIBA Masayoshi SAGA UNIVERSITY, DEPARTMENT OF SOCIAL MEDICIEN, ASSOCIATE PROFESSOR, 医学部・社会医学, 助教授 (60184628)
HARA Kunio NATIONAL CANCER CENTER, INSTITUTE FOR SCIENCE OF LABOUR RESEARCH DIVISION, GROUP LEADER, 研究部, 研究グループ長 (40250047)
YAMANO Yuko SHOWA UNIVERSITY, DEPARTMENT OF HYGIEN, LECTURER, 医学部・衛生学, 講師 (30167580)
|
|---|
| Project Period (FY) |
2003 – 2004
|
| Keywords | ENVIRONMENTAL EPUDEMIOLOGY / MOLECULAR EPIDEMIOLOGY / BIOMARKERS / ENVIRONMENTAL CARCINOGENS / POLYCYCLIC AROMATIC HYDROCARBONS / DNA ADDUCTS |
|---|
| Research Abstract |
THE OBJECT OF THIS STUDY IS TO ESTABLISH A JOB-BIOMARKER MATRIX. THIS MATRIX WILL SERVE AS EXPOSURE ASSESSMENT IN A LARGE-SCALE EPIDEMIOLOGIC STUDY OF COKE OVEN WORKERS TO ESTIMATE CANCER RISK OF POLYCYCLIC AROMATIC HYDROCARBONS. WE CONDUCTED QUESTIONNARE SURVEY AND COLLECTED URINE SAMPLES OF 1200 WORKERS AND OTHER COHORT MEMBERS DURING THE STUDY PERIOD. ANALYSYS OF METABOLITES OF POLYCYCLIC AROMATIC HYDROCARBONS, TWO-RING, THREE RING, FOUR-RING, IS ON-GOING
|
