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2004 Fiscal Year Final Research Report Summary

Epidemiological survey on dural arteriovenous fistulas in Japan.

Research Project

Project/Area Number 15591512
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Cerebral neurosurgery
Research InstitutionTOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY

Principal Investigator

KUWAYAMA Naoya  Toyama Medical and Pharmaceutical University, University Hospital, instructor, 附属病院, 講師 (30178157)

Co-Investigator(Kenkyū-buntansha) KUBO Michiya  Toyama Medical and Pharmaceutical University, Faculty of Medicine, Assistant Professor, 医学部, 助手 (10234486)
Project Period (FY) 2003 – 2004
Keywordsdural arteriovenous fistula / epidemiological survey / incidence
Research Abstract

Nationwide survey was carried out on the epidemiological aspect of dural arteriovenous fistulas (dAVFs) in Japan. The first questionnaire was sent to 1236 neurosurgical clinics (A or C-class clinics registered by the Japan Neurosurgcal Society) to ask the number of patients experienced between 1998-2002. 1815 cases were collected from 338 clinics. Location was the cavernous sinus (CS) in 46% of cases, transverse-sigmoid sinus (ITS) in 28%, spinal cord in 5.8%, superior sagittal sinus (SSS) in 5.3%, anterior cranial base (ACB) in 4.3%, craniocervical junction (CCJ) in 3.3%, tentorium in 3.2%, and others in 4.2%. The detection rate was 0.29 patients (per 100,000 persons per year). Second questionnaire was sent to 112 clinics which responded to the 1^<st> questionnaire, and 1490 cases were collected from 68 clinics. There were 628 men and 850 women and mean age was 62.7±12.7 years. Distribution of the lesion was similar to the prior questionnaire. Female dominancy was noted in CS lesion a … More nd male dominancy in ACB, tentorium, SSS, straight sinus (SS), spinal cord, and CCJ. Initial presentation was occulo-conjunctival symptoms in 65% of the patients, bleeding/infarction in 21%, tinnitus in 20%, increased intracranial pressure in 6%, spinal symptoms in 6%, and hydrocephalus in 0.4%. 6.5% of the patients were asymptomatic. Aggressive lesion was frequently seen in SSS, SS, inferior petrosal sinus and non-aggressive lesion in marginal, cavernous sinus, and condylar vein. Endovascular treatment was selected in 79% of the patients, surgical treatment in 13%, irradiation in 3.4%, and conservative treatment in 11%. Complete angiographic obliteration was obtained in 59% of the patients, subtotal in 16%, partial in 13%. Clinical outcome was full recovery in 54%, improvement in 16%, unchanged in 7%, aggravation in 1.5%, and death in 1.2%. Low obliteration rate and unfavorable outcome were characteristic features in the tentorial lesion, and unfavorable outcome against high obliteration rate in the spinal lesion. Less

  • Research Products

    (6 results)

All 2005 2004

All Journal Article (4 results) Book (2 results)

  • [Journal Article] Hemodynamic status and traetment of aggressive dural arteriovenous fistulas.2005

    • Author(s)
      Kuwayama N
    • Journal Title

      Acta Neurochir (in press)

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 硬膜動静脈瘻の血管内治療における合併症の現状と対策2005

    • Author(s)
      桑山直也
    • Journal Title

      脳卒中の外科 (in press)

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Hemodynamic status and treatment of aggressive dural arteriovenous fistulas.2005

    • Author(s)
      Kuwayama N
    • Journal Title

      Acta Neurochir (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Dural arteriovenous fistulas. -complications and endovascular treatment-.2005

    • Author(s)
      Kuwayama N
    • Journal Title

      Surgery for Cerebral Stroke (Japanese) (in press)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] Dural arteriovenous fistulas.Principles and Advances in Neurological Surgery (Japanese)2005

    • Author(s)
      Kuwayama N
    • Total Pages
      487
    • Publisher
      Nakayama-Shoten Co., Ltd.
    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] 脳神経外科大系(第8巻出血性脳血管障害.硬膜動静脈瘻)(総編集:山浦 晶)2004

    • Author(s)
      桑山直也
    • Total Pages
      487
    • Publisher
      中山書店
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2006-07-11  

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