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2005 Fiscal Year Final Research Report Summary

Restoration and compensation process after hearing and vestibular impairment detected by functional MRI

Research Project

Project/Area Number 15591807
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Otorhinolaryngology
Research InstitutionShiga University of Medical Science

Principal Investigator

HANAMITSU Masakazu  Shiga University of Medical Science, Faculty of Medicine, Assistant Professor, 医学部, 講師 (30346027)

Co-Investigator(Kenkyū-buntansha) SAKURAI Hironori  Shiga University of Medical Science, Faculty of medicine, Research Associate, 医学部, 助手 (60303765)
SUZUKI Mikio  University of the Ryukyus, Faculty of Medicine, Professor (00226557)
Project Period (FY) 2003 – 2005
Keywordsfunctional brain image / functional MRI / hearing disorder / vestibular disease / rehabilitation
Research Abstract

1. The Analysis of hearing impairment
(Method) Twelve patients of sudden deafness and fourteen patients of refractory tinnitus participated in the study. The response of auditory area at contralateral auditory stimulation from high quality non-magnetic MRI headphone was measured. The auditory stimulation was consisted of white-noise (80dB SPL). Measurement was done at same condition and at same stimulation and at five different times : at one week, one month, six months, one year, and two years after onset.
(Result) Three patients were measured at complete five times. Another 23 patients was shorter onset time than 2 year or failure measurement for head movement during MRI. Ten patients were examined both at one week and one year after onset. Patients recovered well had good response of the first auditory area and the auditory sense association area, that were no significant difference with healthy controls. Patients lasted moderate hearing disturbance showed gradually improvement of the response at auditory area.
2. The analysis of vestibular impairment
(Method) Twelve normal subjects and seven patients of vestibular neuritis were examined the response of vestibular stimulation in open and closed eyes respectively. Five patients were successfully analyzed between onset time and after one year from onset. (Results) Four of five patients showed decreased response than normal subjects.

  • Research Products

    (10 results)

All 2006 2005 2004 2003

All Journal Article (9 results) Book (1 results)

  • [Journal Article] Autoantibodies against inner ear proteins in patient with delayed endolymphatic hydrops2006

    • Author(s)
      M.Suzuki, M.Hanamitsu, et al.
    • Journal Title

      Acta Otolaryngol 126/2

      Pages: 117-121

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Autoantibodies against inner ear proteins in patients with delayed endolymphatic hydrops and unilateral juvenile deafness.2006

    • Author(s)
      Suzuki M, Hanamitsu M, Kitanishi T, Kohzaki H, Kitano H
    • Journal Title

      Acta Otolaryngol 126(2)

      Pages: 117-121

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Use of real-time magnetic resonance image guidance in endoscopic sinus surgery2005

    • Author(s)
      M.Suzuki, H.Sakurai, et al.
    • Journal Title

      Minimally Invasive Therapy 14/6

      Pages: 378-384

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Use of real-time magnetic resonance image guidance in endoscopic sinus surgery.2005

    • Author(s)
      Suzuki M, Sakurai H, Kitanishi T, Shimizu T, Nishida Y, Morikawa H, Inubushi T, Kitano H
    • Journal Title

      Minim Invasive Ther Allied Technol 14(6)

      Pages: 376-384

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Successful treatment of disseminated nasal T-cell lymphoma using high-dose chemotherapy and autologus peripheral bloo stem cell transplantation : a case report.2004

    • Author(s)
      H.Kouzaki, M.Suzuki, et al.
    • Journal Title

      Auris Nasus Larynx 31/1

      Pages: 79-83

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Magnetic resonance spectroscopic determination of a neuronal and axonal marker in white matter predicts reversibility of deficits in secondary normal pressure hydrocephalus.2004

    • Author(s)
      A.Shiino, M.Suzuki, et al.
    • Journal Title

      J Neurol Neurosurg Psychiatry 75/8

      Pages: 1141-1148

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Successful treatment of disseminated nasal T-cell lymphoma using high-dose chemotherapy and autologus peripheral blood stem cell transplantation : a case report.2004

    • Author(s)
      Kouzaki H, Kitanishi T, Kitano H, Suzuki M
    • Journal Title

      Auris Nasus Larynx 31(1)

      Pages: 79-83

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Magnetic resonance spectroscopic determination of a neuronal and axonal marker in white matter predicts reversibility of deficits in secondary normal pressure hydrocephalus.2004

    • Author(s)
      Shiino A, Nishida Y, Yasuda H, Suzuki M, Matsuda M, Inubushi T
    • Journal Title

      J Neurol Neurosurg Psychiatry 75(8)

      Pages: 1141-11148

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] International Congress Series 1240, Proceeding of the 17th world congress of the international federation of Oto-Rhino-Laryngological Societies2003

    • Author(s)
      M.Suzuki, M.Hanamitsu, et al.
    • Journal Title

      Elsevier Science, The Netherlands

      Pages: 1481-1485

    • Description
      「研究成果報告書概要(欧文)」より
  • [Book] International Congress Series 1240, Proceedings of the 17the workd congress of the international federation of Oto-Rhino-Laryngological Societies2003

    • Author(s)
      M.Suzuki, M.Hanamitsu, et al.
    • Total Pages
      1481-1485
    • Publisher
      Elsevier Science, The Netherlands
    • Description
      「研究成果報告書概要(和文)」より

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Published: 2007-12-13  

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