Asymmetric Synthesis of Chiral Transition-Metal Complexes by Stereoselective Organic Reactions and Their Application

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H03805
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: The University of Tokushima
• Principal Investigator: Ogasawara Masamichi 徳島大学, 大学院社会産業理工学研究部(理工学域), 教授 (70301231)
• Co-Investigator(Kenkyū-buntansha): 高橋 保 北海道大学, 触媒科学研究所, 教授 (30163273)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 面不斉 / オレフィン・メタセシス / 不斉合成 / 均一系触媒 / メタロセン / 非対称化 / 不斉配位子 / 有機触媒

Outline of Final Research Achievements

The purposes of this research project is development of novel enantioselective synthetic methods of various chiral transition-metal complexes utilizing well-developed stereoselective organic transformations. The target complexes in this study are potential chiral catalysts, and thus, application of the products in the subsequent "second" asymmetric reactions as chiral catalysts or chiral ligands was also examined. The stereoselective organic transformations used in this study are mainly transition-metal-catalyzed asymmetric reactions, but other stoichiometric asymmetric processes are also used. Through this study, we have successfully established multiple methods of preparing various planar-chiral transition-metal complexes in highly enantiomerically enriched forms.

Free Research Field

有機金属化学