2017 Fiscal Year Final Research Report
Developmen of Catalytic Decarboxylation and Decarbonylation Reactions of Esters
| Project/Area Number |
15H03811
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Osaka University |
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Principal Investigator |
Tobisu Mamoru 大阪大学, 工学研究科, 教授 (60403143)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 遷移金属触媒 / 脱カルボニル化 |
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| Outline of Final Research Achievements |
Decarbonylation of ketones is a challenging transformation becasue it requires the cleavage of carbon-carbon bonds. All reported methods for decarbonylation of simple ketones use a stoichiometric amount of rhodium catalysts. In this study, we found the first nickel system that can promote decarbonylation of simple ketones. In addition, nickel-catayzed decarboxylation of aryl carbamates, leading to the formation of arylamines was developed.
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| Free Research Field |
有機合成化学
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