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2017 Fiscal Year Final Research Report

Analysis of implantaion process by using Sox17 heterozygous mouse

Research Project

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Project/Area Number 15H04282
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Laboratory animal science
Research InstitutionTokyo Medical and Dental University

Principal Investigator

KANAI Masami  東京医科歯科大学, 統合研究機構, 教授 (70321883)

Co-Investigator(Kenkyū-buntansha) 平手 良和  東京医科歯科大学, 統合研究機構, 講師 (70342839)
Project Period (FY) 2015-04-01 – 2018-03-31
Keywords着床 / 不妊 / マウス / Sox17
Outline of Final Research Achievements

Few basic and systematic research has been done for maternal implantation process of fertilized embryo which is considered to be the factor in the pregnancy failure. In this study, we have done the pathological analysis by using female Sox17 heterozygous mouse. From the result of microarray analysis using endometrial epithelium from female Sox17 heterozygous mouse, we have selected that the gene group in which the signal ratio was significantly decreased as compared with the wild type.

Free Research Field

実験動物学

URL: 

Published: 2019-03-29  

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