Epigenetic regulation of intragenic transposon in plants

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H04405
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Genetics/Chromosome dynamics
• Research Institution: Okinawa Institute of Science and Technology Graduate University
• Principal Investigator: Saze Hidetoshi 沖縄科学技術大学院大学, 植物エピジェネティクスユニット, 准教授 (70510006)
• Research Collaborator: LE TuNgc 沖縄科学技術大学院大学, 植物エピジェネティクスユニット (30748249) ; Miyazaki Yuji 沖縄科学技術大学院大学, 植物エピジェネティクスユニット (40708773)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: エピジェネティクス / トランスポゾン / 植物ゲノム

Outline of Final Research Achievements

Genomes of vertebrates and plants contain a substantial number of transposable elements (TEs), which are often inserted in genic regions. In this study, we aimed to analyze genome-wide distribution of transposable elements in the model plant Arabidopsis thaliana. We showed that about 3% of TEs are intragenic, especially are inserted in intronic regions. Further study showed that epigenetic silencing of intronic repeats requires RNA-directed DNA methylation pathway, MET1 and DDM1.

Free Research Field

エピジェネティクス