Improving the tolerance to heat stress in animals through integrating control of host and gut microbiota with improved feed ingredients

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H04582
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Animal production science
• Research Institution: Tohoku University
• Principal Investigator: TOYOMIZU Masaaki 東北大学, 農学研究科, 教授 (80180199)
• Co-Investigator(Kenkyū-buntansha): 大塚 彰 鹿児島大学, 農水産獣医学域農学系, 教授 (10233173) ; 陶山 佳久 東北大学, 農学研究科, 准教授 (60282315) ; 喜久里 基 東北大学, 農学研究科, 准教授 (90613042)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: ストレス制御 / タンパク質分解制御 / 免疫能制御 / 腸内細菌叢制御

Outline of Final Research Achievements

The objectives of this research are to clarify the mechanism underlying decreasing body weight and feed efficiency in broiler chickens exposed to heat stress, and to develop feed ingredients to improve the reduced performance. Heat exposure to chickens was found to induce increased proteolysis of skeletal muscles via more mitochondrial ROS generation and decreased CD3-positive cell in the spleen so that metabolic and immune systems remarkably enhance energy requirement to maintain homeostasis. Streptococcus appears to be the less dominant genus in the ileum of heat-stressed chickens. Feeding diets supplemented with cashew nut shell liquid (CNSL) causes broiler chicken to alleviate reductions of body weight and feed intake when exposed to heat, partially via control of intestinal immune-related gene expression.

Free Research Field

動物栄養生化学