2017 Fiscal Year Final Research Report
Species-dependent neural function organized by non-coding RNAs
| Project/Area Number |
15H04603
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Integrative animal science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 種特異的 / 転写因子 / ノンコーディングRNA / DNA脱メチル化 / 神経幹細胞 |
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| Outline of Final Research Achievements |
Vast majority of the fundamental research projects on the mammalian brain utilize the mouse systems. However, morphological and functional differences between primates and rodents evidently exist, and therefore, the molecules that underlie the generation of the differences need be identified. In this study, focusing on the promoter-associated non-coding RNAs (pancRNAs), the comprehensive databases have been made for 5 different mammalian species. Now functional pancRNAs are being screened, that potentially differentiate the neural stem cell behaviors depending on species.
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| Free Research Field |
分子遺伝学
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