2017 Fiscal Year Final Research Report
Analysis of molecular mechanisms of retinal neuron development
| Project/Area Number |
15H04669
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
General anatomy (including histology/embryology)
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Keywords | 網膜 / 細胞分化 / 視覚 / 転写因子 / エピジェネテティック |
|---|
| Outline of Final Research Achievements |
We have studied molecular mechanisms underlying retinal photoreceptor development, synapse formation, and retinal degeneration. In the current study, as a model system to study vertebrate central nervous system development, we have analyzed cell fate determination of retinal photoreceptor cells. We found that transcriptional regulation and epigenetic mechanisms play crucial roles in retinal neuronal differentiation and maturation.
|
| Free Research Field |
神経発生学
|
