2017 Fiscal Year Final Research Report
Molecular structure design for microbial biosurfactant
| Project/Area Number |
15H05338
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Environmental conscious materials and recycle
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| Research Institution | Kitami Institute of Technology |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 酵母 / バイオサーファクタント / 界面活性剤 / 表面張力 / 液晶 |
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| Outline of Final Research Achievements |
We focused a smut fungi Pseudozyma hubeiensis as cell factory for producing mannosylerythritol lipids (MEL), which are attractive material as a next generation eco-frendly surface active reagenet. Using genetics and metabolic engineering, non-natural MEL was attempted to produced selectively and efficently by the mutants. Deacetylated MEL (MEL-D) was synthesized by a acetyltransferase-knock out mutant, and was characterized as a surfactant. Furthermore, a novel tryacylated MEL-D was also synthesized.
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| Free Research Field |
生物化学工学
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