2016 Fiscal Year Final Research Report
Studies on Metastasis of Colon Cancer Using Mouse Models
Project/Area Number |
15H05574
|
Research Category |
Grant-in-Aid for Young Scientists (A)
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Allocation Type | Single-year Grants |
Research Field |
Tumor biology
|
Research Institution | The University of Tokyo |
Principal Investigator |
|
Research Collaborator |
Yamanashi Yuji 東京大学, 医科学研究所, 教授 (40202387)
|
Project Period (FY) |
2015-04-01 – 2017-03-31
|
Keywords | 腸管腫瘍 / 悪性化 / モデルマウス |
Outline of Final Research Achievements |
Most malignant tumor deaths are caused by metastasis with tissue invasion capacity of tumor cells. We previously developed a new mouse model for intestinal malignant tumors. In this study, we demonstrate that tumor progression in these model mice is regulated by tumor microenvironment. Our finding may open new horizons in research of tumor progression and treatment of malignant tumors.
|
Free Research Field |
腫瘍生物学
|