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2016 Fiscal Year Final Research Report

Studies on Metastasis of Colon Cancer Using Mouse Models

Research Project

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Project/Area Number 15H05574
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Tumor biology
Research InstitutionThe University of Tokyo

Principal Investigator

Arimura Sumimasa  東京大学, 医科学研究所, 助教 (60552015)

Research Collaborator Yamanashi Yuji  東京大学, 医科学研究所, 教授 (40202387)
Project Period (FY) 2015-04-01 – 2017-03-31
Keywords腸管腫瘍 / 悪性化 / モデルマウス
Outline of Final Research Achievements

Most malignant tumor deaths are caused by metastasis with tissue invasion capacity of tumor cells. We previously developed a new mouse model for intestinal malignant tumors. In this study, we demonstrate that tumor progression in these model mice is regulated by tumor microenvironment. Our finding may open new horizons in research of tumor progression and treatment of malignant tumors.

Free Research Field

腫瘍生物学

URL: 

Published: 2018-03-22  

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