2016 Fiscal Year Final Research Report
Molecular mechanisms that regulates the localization of organelles
Project/Area Number |
15H06033
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Single-year Grants |
Research Field |
Cell biology
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Research Institution | Tohoku University |
Principal Investigator |
Niwa Shinsuke 東北大学, 学際科学フロンティア研究所, 助教 (30714985)
|
Project Period (FY) |
2015-08-28 – 2017-03-31
|
Keywords | 細胞生物学 / 神経科学 |
Outline of Final Research Achievements |
I have started to analyze molecular mechanisms that regulate the localization of organelles in neurons. I have obtained following results: (1) I have cloned a new gene called ift-139 that is required for the intraflagellar transport (IFT) (Niwa et al. Scientific reports, 2016) (2) I hace clarified a molecular mechanism of the autoinhibition of the axonal transport motor, UNC-104/KIF1A (Niwa et al., Cell Reports, 2016)
|
Free Research Field |
細胞生物学
|