2016 Fiscal Year Final Research Report
The analysis of lymphocyte function against biofilm formation in chronic wound
| Project/Area Number |
15H06052
|
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| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Fundamental nursing
|
|---|
| Research Institution | Tohoku University |
|---|
Principal Investigator |
|
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| Project Period (FY) |
2015-08-28 – 2017-03-31
|
| Keywords | 創傷治癒 / 感染 / リンパ球 |
|---|
| Outline of Final Research Achievements |
Pseudomonas aeruginosa is frequently isolated from chronic wounds.NKT cells play an important role in various aspects of the regulation immune responses, including protection against bacterial infections. However, it is not fully understood how this lymphocyte is involved in the host defense against P. aeruginosa wound infection. In the present sudy,we elucidated the role of NKT cells in clearance of P. aeruginosa from the wound. NKT cell-deficient mice showed impaired clearance of P. aeruginosa.
These results indicate that NKT cells may be involved in the clearance of P. aeruginosa from wounds.
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| Free Research Field |
基礎看護学
|
