2017 Fiscal Year Final Research Report
Classification of oligomeric proteins by secondary structures of contact surface and release of database
| Project/Area Number |
15K00409
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Life / Health / Medical informatics
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| Research Institution | Soka University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 蛋白質複合体 / 相互作用面 / 二次構造 / 分類 |
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| Outline of Final Research Achievements |
In research on life phenomena, utilization of three-dimensional structural data of oligomeric protein is very effective. In this study, the structure of each amino acid on the contact surface of the protein complex was divided into three types, and the number of pairs of structure types in contact between the two contact surfaces was investigated. In addition, we could classify the complex by expressing the ratio of the structure pairs of the whole contact surfaces as a 6 - digit number. We also developed a website OLIGAMI that can browse this classification information. As a result, it was possible to search from both aspects of the structure of the whole protein and the features of the contact surface.
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| Free Research Field |
蛋白質構造科学
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