Mathematical Understanding of lnformation Processing Mechanism in the Brain by lnteraction of Glial and Neuronal Networks

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K00417
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Life / Health / Medical informatics
• Research Institution: The Institute of Statistical Mathematics
• Principal Investigator: Tamura Yoshiyasu 統計数理研究所, データ科学研究系, 教授 (60150033)
• Co-Investigator(Kenkyū-buntansha): 染谷 博司 東海大学, 情報理工学部, 准教授 (00333518) ; 越久 仁敬 兵庫医科大学, 医学部, 教授 (20252512) ; 岡田 泰昌 独立行政法人国立病院機構村山医療センター(臨床研究部), 電気生理学研究室, 室長 (80160688)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: アストロサイト / カルシウムイメージング / 呼吸リズム

Outline of Final Research Achievements

Astrocytes in the brain stem have an important role in respiratory rhythm formation in coordination with neurons. It was found that astrocytes play an important role in hypoxic respiratory response mechanism as hypoxic sensors in the brain.
We developed a simulation model by coupling a neuronal network model and an astrocytic oscillator model. We attempted to reveal roles of astrocytes in respiratory rhythm formation by simulations.

Free Research Field

計算統計学