Fasting-related response of skeletal muscles with exercise

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K01640
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Sports science
• Research Institution: Hiroshima Shudo University
• Principal Investigator: Ogata Tomonori 広島修道大学, 人間環境学部, 教授 (30434343)
• Co-Investigator(Kenkyū-buntansha): 大石 康晴 熊本大学, 教育学部, 教授 (10203704)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 骨格筋 / 絶食 / 応答

Outline of Final Research Achievements

The purpose of this study is to determine the effects of fasting to exercise-related physical response and adaptation. This study designed two exercise models using treadmill running under fasting condition. One is low intensity endurance exercise (30 m/min, 50min), and the other is high intensity exercise after 24 hours fasting. We analyzed the expression of autophagy marker (LC3-II), heat shock proteins (HSPs) and mTOR signaling pathway in plantaris and soleus muscles. In plantaris muscle, LC3-II was increased by 24 hours fasting, but no additional change with both endurance and high intensity exercise. There was no effect on expression of HSP72 and mTOR signaling by fasting in both types of exercise model.

Free Research Field

運動生理学