Photothermal nano heater for medicine applications

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K04679
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Thin film/Surface and interfacial physical properties
• Research Institution: The University of Tokushima
• Principal Investigator: Yanagiya Shin-ichiro 徳島大学, 大学院社会産業理工学研究部(理工学域), 助教 (40314851)
• Co-Investigator(Kenkyū-buntansha): 後藤 信夫 徳島大学, 大学院社会産業理工学研究部(理工学域), 教授 (60170461)
• Research Collaborator: SEKIMOTO Naoya ; TAKAHATA Toshihiko ; MATSUOKA Hiroya ; MATSUMURA Hisatomo
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 金ナノ粒子 / 表皮角層 / 熱プラズモニクス / 光熱ダイナミクス / その場観察法

Outline of Final Research Achievements

The main purpose of the study is to achieve the photothermal devices for the nano heating of biological tissues. We reported the following findings and demonstrations as nano material science: ① the fabrication of micro glass beads coated with gold nanoparticles (AuNP) and the investigations for their photothermal effects, ② the microscopic Raman study of graphene on 4H-SiC two-dimensionally enhanced by AuNPs, and ③ optical properties of titanium dioxide sputtered film deposited on two-dimensionally assembled AuNP. And the achievements for photothermal bubbles are as follows: ④ micro- and nano-scopic study of fine bubbles generated by photothermal of AuNPs and ⑤ growth and shrinkage of microbubbles in water-alcohol mixture generated by photoexcitation of AuNP. In addition, we also reported the followings as biomechanical science: ⑥ the mechanical properties of stratum corneum in glycerin solution and ⑦ nano mechanical properties of corneocyte by atomic force microscopy.

Free Research Field

光ナノ材料物性、ソフト界面科学