Exploration of universal methodology for high activity and insoluble catalyst development

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K05510
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: Yamada Yoichi M. A. 国立研究開発法人理化学研究所, 環境資源科学研究センター, 副チームリーダー (50317723)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 高分子金属触媒 / 高分子触媒 / 高活性 / 再利用性 / クロスカップリング / 鈴木-宮浦反応 / パラジウム触媒

Outline of Final Research Achievements

In order to develop a novel highly active insoluble supramolecular polymer - palladium catalyst, preparation of highly hydrophilic - lipophilic chain polypyrimidine was investigated. A polymer pyrimidine having a pentyl group, a methyl group, and a proton introduced into the main chain polymer was prepared. As a result of examining the molecular convolution of this polymer and ammonium palladate, we succeeded in the creation of a supramolecular polymer pyrimidine-palladium catalyst which is insoluble in both water and organic solvent.
This catalyst is effective for the Suzuki-Miyaura reaction with phenyl boronic acid based on a variety of aryl chlorides having low reactivity. The reaction proceeds efficiently in water with a catalytic amount of 400 mol ppm Pd.

Free Research Field

有機合成化学