2017 Fiscal Year Final Research Report
Development of multicolor saccharide sensor array and its application for multi-target sensing systems
| Project/Area Number |
15K05526
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Kitami Institute of Technology |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
青木 寛 国立研究開発法人産業技術総合研究所, エネルギー・環境領域, 主任研究員 (00392580)
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| Project Period (FY) |
2015-10-21 – 2018-03-31
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| Keywords | ボロン酸 / センサ / 過酸化水素 / 次亜塩素酸 / 薄膜 |
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| Outline of Final Research Achievements |
Molecular structure of the boronic acid monomer was modified to improve glucose sensitivity. Saccharide sensors were prepared on a pattern-printed microscope slide as a thin film containing newly synthesized boronic acid monomer units. By examining responsiveness against saccharides, it was found that introduction of hydroxylmethyl group onto the aromatic ring of the boronic acid is effective for sensitivity improvement.
The boronic acid-containing thin film was applied for sensing of hydrogen peroxide. By changing monomer composition and dye, variety of color change was realized.
Hypochlorite sensors were also developed. After thoroughly tuning functionality of the thin film, distinct color change appeared.
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| Free Research Field |
分子認識化学
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