2017 Fiscal Year Final Research Report
Evaluation of joint prosthesis rubbing surface with low friction property by clarifying adsorption mechanisms of protein molecules
| Project/Area Number |
15K05765
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Design engineering/Machine functional elements/Tribology
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| Research Institution | Teikyo University (2017)
Kyushu University (2015-2016) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 人工関節 / 境界潤滑 / 蛋白質 / 低摩擦 |
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| Outline of Final Research Achievements |
It was pointed out that albumin and g-globulin included in natural synovial fluid can form cooperative film on joint prosthesis material and as a result the adsorbed film make friction low. In this study, friction and adsorption properties of albumin and g-globulin were investigated to clarify the mechanisms of maintaining low friction.
Albumin showed low friction property and g-globulin showed high adsorption amount. The different property of two kind of protein indicates albumin molecule exhibits low friction of joint prosthesis and g-globulin protects joint prosthesis material from wear. These results suggest that adsorbed protein film shows low friction due to different properties of albumin and g-globulin forming cooperative adsorbed film.
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| Free Research Field |
バイオトライボロジー
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