2017 Fiscal Year Final Research Report
Development of next generation bioactive titanium
| Project/Area Number |
15K06482
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAGUCHI Seiji 中部大学, 生命健康科学部, 講師 (50726198)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Keywords | 生体活性チタン / ストロンチウム / マグネシウム / 骨芽細胞 |
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| Outline of Final Research Achievements |
Bioactive titanium metals induced strontium ions or magnesium ions enhanced expression of integrin β1 and osteogenic differentiation in in vitro studies using MC3T3-E1 cells. In rabbit in vivo studies, they also provided greater biomechanical strength between bone and bioactive titanium metals. Because induced strontium ions were detected in the bone near the implant, strontium ions were released and influenced the bone near the implant.
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| Free Research Field |
整形外科学
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