Development of Reactive Separation Technology Employing the Synergy of Sub/Supercritical H2O-CO2 System

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K06559
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Reaction engineering/Process system
• Research Institution: Kumamoto University
• Principal Investigator: QUITAIN ARMANDO 熊本大学, グローバル教育カレッジ, 教授 (50504693)
• Co-Investigator(Renkei-kenkyūsha): KIDA Tetsuya 熊本大学, 大学院先端科学研究部, 教授 (70363421) ; SASAKI Mitsuru 熊本大学, パルスパワー科学研究所, 准教授 (40363519)
• Research Collaborator: COCERO Maria Jose Valladolid University, Department of Chemical Engineering and Environmental Technology, Professor ; YUSUP Suzana Universiti Teknologi PETRONAS, Department of Chemical Engineering, Professor ; Laosiripojana Navadol King Mongkut's University of Technology Thonburi, The Joint Graduate School of Energy and Environment(JGSEE), Professor ; Auresenia Joseph De La Salle University, Department of Chemical Engineering, Professor ; Dugos Nathaniel De La Salle University, Department of Chemical Engineering, Professor
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: supercritical CO2 / subcritical water / hydrolysis / bioflavonoids / aglycone / green solvent / reactive separation / synergy

Outline of Final Research Achievements

We have succeeded in hydrolyzing hesperidin (HPD) to hesperetin (HPT) in the temperature range of 150 to 200 ℃, and pressures of 15 to 25 MPa obtaining about 2-fold increase in yield compared to the conventional method using our proposed novel reactive separation process utilizing the synergy of SCCO2 and subcritical H2O. Simultaneous and selective separation of HPT was achieved by simply passing SCCO2 through the reaction products. International collaboration has started which includes Valladolid University on the use of visual cell and Raman spectroscopy. The application of this novel approach was further extended to include conversion of biomass to platform chemicals and fuels in collaboration with Universiti Teknologi PETRONAS, University of the Philippines and De La Salle University. Our future studies will include elucidating the reaction mechanism taking place in the proposed system using quantum calculation techniques and molecular dynamic simulations.

Free Research Field

超臨界流体工学及びマイクロ波技術