Development of isolation method for endophytic actinomycetes using plant model and search for microbial resources

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K06936
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Conservation of biological resources
• Research Institution: Kitasato University
• Principal Investigator: Matsumoto Atsuko 北里大学, 感染制御科学府, 准教授 (20300759)
• Co-Investigator(Kenkyū-buntansha): 中島 琢自 北里大学, 北里生命科学研究所, 特任准教授 (40526216)
• Co-Investigator(Renkei-kenkyūsha): TAKAHASHI Yoko 北里大学, 北里生命科学研究所, 研究員 (80197186) ; SHIOMI Kazuro 北里大学, 感染制御科学府, 教授 (40235502)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 放線菌 / 植物内生菌 / 未利用微生物 / 微生物資源 / 分類

Outline of Final Research Achievements

There are many untapped endophytic actiomycetes. In order to isolate and culture them as source of new bioactive compounds, new isolation method using cultured cell of plant was developed. Endophytic actinomycete strain, which requires cultured cell of plant for growth was isolated by this method.
It was showed by taxonomic study that isolated endophytic actinomycetes were three new species belonging the genus Kibdelosporangium, and the 22-membered macrolides, hamuramicin was found in the cultured broth of endophytic actinomycetes Allostreptomyces sp. K12-0794.

Free Research Field

応用微生物学