2017 Fiscal Year Final Research Report
Evaluation of cytotoxicity by Surface Plasmon Resonance (SPR) sensor using cell-immobilized sensor chip
| Project/Area Number |
15K07457
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Fukuoka Women's University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
石川 洋哉 福岡女子大学, 国際文理学部, 准教授 (00325490)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 細胞固定化センサ / 毒性評価 / SPR |
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| Outline of Final Research Achievements |
In this research, we tried to develop a method for evaluating cytotoxicity by Surface Plasmon Resonance (SPR) sensor using cell-immobilized sensor chip. As a result, 1) a method of immobilizing cells on the sensor chip gold film was constructed, 2) the response of the cell to the verotoxin (macromolecule) can be measured as a SPR signal change, 3) the cell hydrogen peroxide (Low molecular weight) can be measured as SPR signal change.
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| Free Research Field |
食品衛生学
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