2017 Fiscal Year Final Research Report
Effects of chemically modified synthetic microRNA-205 on spontaneous canine melanoma.
Project/Area Number |
15K07742
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Veterinary medical science
|
Research Institution | Gifu University |
Principal Investigator |
MORI Takashi 岐阜大学, 応用生物科学部, 教授 (40402218)
|
Co-Investigator(Kenkyū-buntansha) |
野口 俊助 大阪府立大学, 生命環境科学研究科, 准教授 (10701295)
酒井 洋樹 岐阜大学, 応用生物科学部, 准教授 (40283288)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Keywords | microRNA / melanoma / dog |
Outline of Final Research Achievements |
The purpose of this study was to evaluate effects of chemically modified synthetic microRNA-205 (miR-205) on spontaneous canine melanoma. A total of 9 dogs were included in this study. 4 cases obtained complete remission (CR). One case was partial response (PR), and 3 cases were stable disease (SD). 2 cases were progressive disease (PD). There were not any side effects in all cases during miR-205 treatment.
|
Free Research Field |
獣医臨床腫瘍学
|