2017 Fiscal Year Final Research Report
Development and applications of novel methodologies for the construction of asymmetric tetrasubstituted carbon stereocenters
| Project/Area Number |
15K07860
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 有機合成化学 / 不斉四置換炭素 / 触媒 / 環境調和型反応 |
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| Outline of Final Research Achievements |
In this research, we achieved the design of novel highly active catalysts based on detailed mechanistic studies and their application to the synthesis of asymmetric tetrasubstituted carbon stereocenters, resulted in the construction of a new chemical library of amino acid derivatives with tetrasubstituted carbon stereocenters.
In addition, we succeeded in developing environmentally friendly new catalytic asymmetric tetrasubstituted carbon synthesis using unprotected imines and paved the new way for the synthesis of unprotected amines.
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| Free Research Field |
有機合成化学
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