2017 Fiscal Year Final Research Report
Study on construction and practical application of inhalation system suitable for alveolar regeneration medicine
| Project/Area Number |
15K07901
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Physical pharmacy
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | ドラックデリバリーシステム / 吸入システム / 再生医療 |
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| Outline of Final Research Achievements |
To develop the drug for alveolar regeneration based on inducing differentiation of alveolar progenitor cells, we aimed to find efficient delivery system of the drug to the site of action. Using the drug carrier ssPalm, the drug for alveolar regeneration showed alveolar repairing effect efficiently. The suitable particle size, enclosed capacity, and the minimum dose of drug were determined. Furthermore, ssPalm, which repaired collapsed alveoli, showed rapidly escaping from an endosome in a cell and we showed the possibility of making inhalations for clinical application.
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| Free Research Field |
物理系薬学
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