Morphological study of the vagus nerve and pelvic nerve plexus branches of the parasympathetic nervous distributed in the colon

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08143
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General anatomy (including histology/embryology)
• Research Institution: Iwate Medical University
• Principal Investigator: YAN JUN 岩手医科大学, 医学部, 准教授 (20316350)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 自律神経 / 上下腹神経叢 / 下下腹神経叢 / 逆行性標識 / ヒト / ラット / Flk1マウス

Outline of Final Research Achievements

Visceral nerve fibers distributed in the human colon is still unclear. There was no difference in "distribution pattern" of the superior hypogastric plexus distributed in the colon of humans and rats. Labeling the superior hypogastric plexus of the rat suggested that the peripheral distribution in the colon is very extensively. Since neurons of these visceral nerve fibers were not observed in the sacral part of spinal cord, but were observed only in the lumbar sympathetic ganglia, it seems that the characteristic of this plexus fiber of rat is only "sympathetic nerve fiber". The parasympathetic fibers derived from the pelvis distributed in the colon are presumed to be components of the "inferior hypogastric plexus". The parasympathetic nerve fiber component distributed in the midgut was observed with transgenic mouse Flk1 early embryo, and the VIP staining method was also established.

Free Research Field

臨床解剖学