Worksite-based epidemiological study for examining utility of serum polyunsaturated fatty acid levels for predicting new-onset metabolic syndrome in workingmen.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08752
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Nippon Medical School
• Principal Investigator: Otsuka Toshiaki 日本医科大学, 医学部, 准教授 (80339374)
• Co-Investigator(Kenkyū-buntansha): 川田 智之 日本医科大学, 大学院医学研究科, 大学院教授 (00224791) ; 小谷 英太郎 日本医科大学, 医学部, 講師 (10287708)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: メタボリック症候群 / 多価不飽和脂肪酸 / 疫学研究

Outline of Final Research Achievements

Metabolic syndrome (MetS) is well known to be a major risk factor for cardiovascular disease, not only in Western countries but also in Japan. It is therefore important to prevent new-onset MetS to further support health promotion for Japanese people. We conducted worksite-based epidemiological study to examine whether serum ω-3 polyunsaturated fatty acid levels were predictive of new-onset MetS in Japanese workingmen. However, any polyunsaturated fatty acid levels measured in this study (eicosapentaenoic acid, docosahexaenoic acid, and eicosapentaenoic acid/arachidonic acid ratio) did not show significant predictive values for new-onset MetS in this study population. Further studies are needed to elucidate the longitudinal association between ω-3 polyunsaturated fatty acid levels and the risk of new-onset MetS.

Free Research Field

生活習慣病の予防、循環器病予防医学