Molecular nutritional study for prevention of prostate cancer

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08779
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: Kumamoto University
• Principal Investigator: Katoh Takahiko 熊本大学, 大学院生命科学研究部(医), 教授 (70169506)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 前立腺がん / 栄養 / 食物摂取頻度調査票 / 分子疫学 / ヘテロサイクリックアミン / 遺伝子多型

Outline of Final Research Achievements

We conducted a comprehensive molecular nutrition epidemiological analysis to clarify the risk factors for prostate cancer in Japanese population. These finding indicate that high heterocyclic aromatic amines intake is a risk factors of prostate cancer in Japanese men, and that the genotypes of N-acetyltransferase 2, Cytochrome P450CYP1A1, and Cytochrome P4501A2 may affect the degree of cancer risk via changes in heterocyclic aromatic amines -metabolizing enzymes.

Free Research Field

公衆衛生学