Decrease in the prevalence of extended-spectrum cephalosporin-resistant Salmonella

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08794
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Hygiene and public health
• Research Institution: National Institute of Infectious Diseases
• Principal Investigator: Murakami Koichi 国立感染症研究所, 感染症疫学センター, 室長 (70446839)
• Research Collaborator: SHIGEMURA Hiroaki 福岡県保健環境研究所 (50761540)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: サルモネラ / 薬剤耐性 / 鶏肉 / Infantis / 血清型 / 基本再生産

Outline of Final Research Achievements

Decreasing was detected in the prevalence of extended-spectrum cephalosporin-resistant Salmonella following cessation of ceftiofur use by the Japanese poultry industry. Extended-spectrum cephalosporin (ESC)-resistant Salmonella in chicken meat is a significant food safety concern. The prevalence of ESC-resistant Salmonella inchicken meat products increased in Japan between 2005 and 2010. The prevalence of ESC-resistant Salmonella, mainly consisting of AmpC β-lactamase CMY-2-producing isolates, in chicken meat products had increased to 45.5% (10/22) by 2011. However, following the voluntary cessation of ceftiofur use by the Japanese poultry industry in 2012, the prevalence of ESC-resistant Salmonella steadily decreased each year, to 29.2% (7/24), 18.2% (4/22), 10.5% (2/19), and 10.5% (2/19) in 2012, 2013, 2014, and 2015, respectively. Furthermore, no AmpC β-lactamase CMY-2-producing isolates were identified in 2014 and 2015.

Free Research Field

獣医公衆衛生