Effects of pre-heat exposure intake of electrolyte drinks in the rat.

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08869
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Legal medicine
• Research Institution: Mie University
• Principal Investigator: NATA Masayuki 三重大学, 医学系研究科, 教授 (70241627)
• Co-Investigator(Kenkyū-buntansha): 小澤 周二 三重大学, 医学系研究科, 講師 (20379944)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 熱中症 / 電解質飲料 / サイトカイン / 脳 / ラット

Outline of Final Research Achievements

In heatstroke, various organs can be damaged directly by heat exposure, and systemic inflammatory responses can also occur through the development of hypercytokinemia. The purpose of the present study was to elucidate how intake of an electrolyte drink before heat exposure modulates heat exposure-induced damage in a rat model. The results showed that mRNA relating with heat shock protein and cytokine was changed with heat exposure, and intake of an electrolyte drink prior to heat exposure suppressed the changes. These findings suggest that intake of an electrolyte drink before heat exposure reduces the intensity of heat stress to the body, thereby improving heat tolerance.

Free Research Field

法医学