2017 Fiscal Year Final Research Report
Development of new supportive therapy about fatigue mitigation after the cisplatin administration in cancer patients - Carnitine substitution therapy
| Project/Area Number |
15K08903
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General internal medicine(including psychosomatic medicine)
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| Research Institution | Meijo University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
菓子井 達彦 富山大学, 大学院医学薬学研究部(医学), 客員教授 (00313619)
梶浦 新也 富山大学, 大学院医学薬学研究部(医学), 助教 (70456383)
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| Research Collaborator |
IKEZAKI Tomoaki
NITTA Atsumi
MIWA Toshiro
HOSOKAWA Ayumu
YASUDA Hatsuna
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 倦怠感 / カルニチン / がん / 化学療法 / 支持療法 / 緩和医療 |
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| Outline of Final Research Achievements |
In this study, we examined observation to confirm quantitatively whether blood carnitine significantly decreased by the cisplatin dosage, and what carnitine leaked through the whole urine after the cisplatin dosage. This leakage changed parallel to a rise of the β2-microglobulin which was the marker of tubular impairment, we clarified that it was the leakage due to tubular impairment.
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| Free Research Field |
Medical oncology and supportive care
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