Fundamental research for treatment optimization in elderly patients with mesothelioma

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08905
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General internal medicine(including psychosomatic medicine)
• Research Institution: Nagoya University
• Principal Investigator: MASAHIRO MORISE 名古屋大学, 医学部附属病院, 病院助教 (00612756)
• Co-Investigator(Kenkyū-buntansha): 近藤 征史 藤田保健衛生大学, 医学部, 教授 (00378077) ; 安藤 昌彦 名古屋大学, 医学部附属病院, 准教授 (10322736)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 悪性胸膜中皮腫 / 高齢者 / 化学療法 / 消化器毒性

Outline of Final Research Achievements

Chemotherapy induced nausea and vomitting (CINV) can be associated with discontinuation of cisplatin plus pemetrexed/carboplatin plus pemetrexed, which are standard regimen for advanced malignant mesothelioma. Based on our research, pemetrexed regimen showed higer indcidence of CINV compared to non-pemetrexed 3rd generation anticancer drugs.

Free Research Field

呼吸器内科学