2017 Fiscal Year Final Research Report
Relationship between heart failure and systemic inflammatory disease chronic obstructive pulmonary disease and clarification of vicious cycle factor
| Project/Area Number |
15K09090
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular medicine
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 心不全 / 慢性閉塞性肺疾患 / 全身性炎症疾患 / 肺高血圧症 / 悪液質 |
|---|
| Outline of Final Research Achievements |
Chronic obstructive pulmonary disease (COPD) has a great influence on cardiovascular diseases. It has been reported that the prognosis of heart failure patients is markedly reduced by the COPD, but there are many uncertainties about the details of the vicious circle. We examined the effects of COPD on cardiac function using samples obtained from patients with heart failure combined with COPD using echocardiography and biomarkers. We clarified that pulmonary hypertension is complicated irrespective of degree of respiratory dysfunction. In addition, since heart failure and COPD are frequent in elderly people and are often in cachectic state, we also examined the relationship with nutritional indicators and clarified the relevance.
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| Free Research Field |
循環器内科学
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