Development of intravascular ultrasound for the evaluation of coronary stress

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09119
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Cardiovascular medicine
• Research Institution: Gifu University
• Principal Investigator: Kawasaki Masanori 岐阜大学, 医学部附属病院, 准教授 (50214630)
• Research Collaborator: TANAKA Shinichiro ; YAGAMI Hiroyuki
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 血管内超音波 / 力学的ストレス / 冠動脈 / 動脈硬化

Outline of Final Research Achievements

Recently, two-dimensional speckle tracking echocardiography has been used to evaluate heart function. We applied this technique that is used for the evaluation of heart function to coronary arteries. The velocity vectors in the two-dimensional plane are displayed throughout the cardiac cycle, representing displacement of the speckles in relation to each other along the internal contour of coronary artery. Using this system, time-area curve can be automatically and promptly provided. We named this technique speckle tracking intravascular ultrasound (ST-IVUS). We determined the feasibility of evaluating strain and area of coronary plaque using ST-IVUS. There were strong correlation between luminal area by manual measurement and that by ST-IVUS measurement at both end-systole (r =0.98, p < 0.001) and end-diastole (r =0.98, p < 0.001). The strains of coronary arteries in the patients with diabetes mellitus.correlated with the level of HbA1c.

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