The elucidation of diabetogenic factors and its interaction in type 2 diabetes

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09403
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Metabolomics
• Research Institution: Kindai University
• Principal Investigator: BABAYA Naru 近畿大学, 医学部, 講師 (10449837)
• Co-Investigator(Kenkyū-buntansha): 池上 博司 近畿大学, 医学部, 教授 (20221062) ; 川畑 由美子 近畿大学, 医学部, 准教授 (80423185) ; 能宗 伸輔 近畿大学, 医学部, 講師 (90460849) ; 廣峰 義久 近畿大学, 医学部, 講師 (30460851)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: NSYマウス / コンソミックマウス / 糖尿病疾患感受性遺伝子

Outline of Final Research Achievements

Type 2 diabetes is multifactorial diseases caused by a complex interaction of multiple susceptibility genes and environmental factors. In this study, we localized the diabetes-related regions in mice. In addition, we constructed the phenotype panel in human. During the course of constructing the panel, a rare case was found and reported (Babaya N, et al., BMC Endocrine Disorders 17、2017、1-6). We also reported the susceptible loci of type 1 diabetes and Grave’s disease (Babaya N, et al., Hum Immunol 78、2017、185-189, and Babaya N, et al., J Clin Endocrinol Metab 100、2015、1976-1983).

Free Research Field

糖尿病