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2017 Fiscal Year Final Research Report

Clarifying the pathogenesis of ABC-DLBCL in a mouse model

Research Project

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Project/Area Number 15K09474
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Hematology
Research InstitutionKyoto University

Principal Investigator

Nishikori Momoko  京都大学, 医学研究科, 講師 (60378635)

Co-Investigator(Renkei-kenkyūsha) IWAI Kazuhiro  京都大学, 大学院医学研究科 細胞機能制御学講座, 教授 (60252459)
Research Collaborator JO Tomoyasu  京都大学, 大学院医学研究科血液・腫瘍内科学
ARIMA Hiroshi  京都大学, 大学院医学研究科血液・腫瘍内科学
Project Period (FY) 2015-04-01 – 2018-03-31
Keywords悪性リンパ腫 / マウスモデル
Outline of Final Research Achievements

To clarify the pathogenesis of ABC-type diffuse large B-cell lymphoma (DLBCL), we generated a mouse lymphoma model by crossing gene-engeneered mice carrying HOIP and mutant MyD88 transgenes. We have found how these genes cooperate with each other during lymphomagenesis.

Free Research Field

血液腫瘍学

URL: 

Published: 2019-03-29  

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