Analyses of pathological conditions, pathogenic molecular epidemiology, and antimicrobial resistance in uterine infections due to group A streptococcus

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09578
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Infectious disease medicine
• Research Institution: Kitasato University
• Principal Investigator: Takahashi Takashi 北里大学, 感染制御科学府, 教授 (00292855)
• Co-Investigator(Renkei-kenkyūsha): YOSHIDA Haruno 北里大学, 大学院感染制御科学府, 助手 (70563386) ; MATSUI Hidenori 北里大学, 大学院感染制御科学府, 講師 (30219373) ; ARAI Kazuaki 北里大学, 北里生命科学研究所, 研究員 (30547386)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 細菌 / 子宮内感染症 / 菌側因子 / 宿主因子 / 薬剤耐性 / 分子疫学

Outline of Final Research Achievements

We selected vaginal discharge-origin isolates of pathogenic group A beta-hemolytic streptococcus, the throat swab-derived strains, and the isolates from severe infectious diseases using the established databases including bacterial information and patient backgrounds, which were collected nationwide. As compared with the microbiological features in the throat-origin isolates, there were significantly characteristic findings in the vagina-derived strains. In addition, we could observe similarities between the microbiological features in the vagina-origin isolates and those in the strains from uterine infections.

Free Research Field

感染症学、臨床微生物学、感染制御学