Development of treatment methods based on the neural substrates associated with chronic fatigue and inattention processing in pediatrics

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09596
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Pediatrics
• Research Institution: Kumamoto University
• Principal Investigator: Joudoi Takako 熊本大学, 医学部附属病院, 助教 (90363522)
• Co-Investigator(Kenkyū-buntansha): 水野 敬 国立研究開発法人理化学研究所, 科学技術ハブ推進本部, チームリーダー (60464616)
• Co-Investigator(Renkei-kenkyūsha): KAWATANI Junko 熊本大学, 医学部附属病院, 非常勤診療医師 (30423669) ; SASAKI Akihiro 国立研究開発法人理化学研究所, 研究員 (10711781)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 小児慢性疲労症候群 / 注意欠如多動症 / 脳科学 / fMRI / 報酬 / 意欲 / 疲労 / 治療

Outline of Final Research Achievements

We investigated the effects of each treatment method in patients with childhood chronic fatigue syndrome (CCFS) and attention deficit hyperactivity disorder (ADHD) evaluated by functions of attention control and reward sensitivity. Although it was difficult to identify the treatments effects using an index of neural activity, the effects of cognitive behavioral therapy and medication treatment could be evaluated using indexes of attention control and autonomic nerve activity, suggesting that these evaluation methods are beneficial.

Free Research Field

医歯薬学